Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity linked to bortezomib, a proteasome inhibitor used in the therapy of several myeloma. Its synthesis or study is very important for guaranteeing the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-one): A important compound during the synthesis of imatinib, a drug that targets distinct varieties of most cancers, which includes Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers like breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates from the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the generation process and making certain superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to take care of breast cancer, and these intermediates are associated with its generation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist Employed in the treatment method of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized (2E)- in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers including ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the procedure of colorectal most cancers and small cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved in the synthesis of adamantane derivatives, which have various applications, which includes antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for variety 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is involved in the synthesis of various gluconic acid derivatives, which can be used in meals, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication used to deal with style two diabetes by inhibiting 2'-Difluoro-2'-deoxycytidine-3' sodium-glucose co-transporter two (SGLT2).